Genistein Attenuates Nonalcoholic Steatohepatitis and Increases Hepatic PPARγ in a Rat Model

Table 1

Summary of histopathological scores in all groups.

Group		Steatosis				Inflammation				Ballooning
		0	1	2	3	0	1	2	3	0	1	2
Control	8	8	—	—	—	8	—	—	—	8	—	—
NASH	8	—	7	—	1	4	2	2	—	—	2	6
NASH + Gen8	8	2	4	1	1	3	3	2	—	2	1	5
NASH + Gen16	7	4	2	1	—	7	—	—	—	3	4	—

Data are expressed as the number of rats presenting each score of histopathology. Levels of steatosis: 0 = <5% of hepatocytes containing fat; 1 = <33% of hepatocytes containing fat; 2 = 33–66% of hepatocytes containing fat; 3 = >66% of hepatocytes containing fat. Levels of inflammation: 0 = normal; 1 = mild; 2 = moderate; 3 = severe. Levels of ballooning degeneration: 0 = no ballooning; 1 = few balloon cells; 2 = many balloon cells.