Hepatoprotective Effect of Terminalia chebula against t-BHP-Induced Acute Liver Injury in C57/BL6 Mice

Figure 4

Antioxidant enzyme and proinflammatory and anti-inflammatory-related genes expression in hepatic tissue. The mice were administered with TCW (50, 100, and 200 mg/kg), gallic acid, or distilled water orally once per day for 5 days. After 18 h of t-BHP injection, livers were removed and mRNA levels of GSH-Sy, GSH-Px, GSH-Rd, SOD-1, SOD-2, and SOD-3 (a) and CAT, iNOS, TNF-α, IL-1β, IL-6, and CYP2E1 (b) in hepatic tissue were determined using real-time PCR. The mRNA levels were normalized to that of β-actin. Data are expressed as the mean ± SD (). ^#, ^##, and ^### compared with the naive group; ^*, ^**, and ^*** compared with the control group.

(a)

(b)