The Effect of Tou Nong San on Transplanted Tumor Growth in Nude Mice

Figure 2

The effects of different dose of TNSE on the growth of LoVo cells-xenografts in nude mice. (a) The tumor volumes were recorded at 2-day intervals. TNSE inhibited the growth of the transplanted tumors, and the volume of the tumors in the TNSE treated group was much smaller than that in the control group (). Data are represented as means ± SD (). (b) Body weight was evaluated at 2-day intervals in all groups. In the control group, the body weights of mice were higher than that in the TNSE treated groups, but there have been no significance among these four groups (). Data are represented as means ± SD (). (c) The xenografts in the four groups at the conclusion of the experiment. A: control (NS), B: TNSE (4 g/kg), C: TNSE (2 g/kg), and D: TNSE (1 g/kg). (d) TNSE could inhibit the growth of the transplanted tumor. With increasing dose, the weight of xenografts decreases. (e) The function of liver and renal. A: control (NS), B: TNSE (4 g/kg), C: TNSE (2 g/kg), and D: TNSE (1 g/kg). Data are represented as means ± SD (). versus Control group; versus Control group.

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