Research Article

Hepatoprotective Effect of Silymarin (Silybum marianum) on Hepatotoxicity Induced by Acetaminophen in Spontaneously Hypertensive Rats

Figure 2

Serum parameters of rats of all groups untreated, treated with APAP (3 g/kg, orally), and pretreated with SLM (200 mg/kg) of MPO activity (a) and NO production (b) were determined 12 h after APAP intoxication. Results represent mean ± SEM of 12 rats per group. N + APAP versus N, N + SLM + APAP versus N + APAP, SHR + APAP versus SHR, and SHR + SLM + APAP versus SHR + APAP.
(a)
(b)