Review Article

Acupuncture to Treat Sleep Disorders in Postmenopausal Women: A Systematic Review

Table 1

List and description of selected studies.

ArticleArticle typeSample description-exp-ctrl/shamTreatment conditionType of treatmentAcupoints, expAcupoints, ctrl Sleep assessmentMain results

Hammes et al., 2014 [38]Case report49-y postmenopausal woman1NA22 sessions, weekly or biweeklyBody and auricular acupunctureSessions 1–6: LI-4, LR-3, CV-6, CV-17, HT-6, KI-6, KI-2, GV-20, auricular: ShenMen, kidney Sessions 7–22: LI-4, LR-3, CV-4, CV-6, CV-17, HT-6, KI-6, GB-41, GV-20, auricular: ShenMen, kidneyNAInsomnia self-reportImprovement

Baccetti et al., 2014 [39]Randomized controlled trialPostmenopausal women, ≥3 hot flushes episodes/day4749Twice a week, during four weeksB
ody acupuncture
Stimulation with star needles in dorsal region C7-T5. Electrostimulation: dispersion (100 cycles/s) on GV-23, CV-22, BL-2, LI-11, and LI-4; tonification (40 cycles/s) on SP-10 and SP-6; and tonification with GV-20, CV-4, CV-6, ST-37, and LR-3None1–4 scale about sleep disorders severityImprovement

Hachul et al., 2013 [35]Randomized controlled trialPostmenopausal women, insomnia99Twice a week, during five weeksBody acupunctureNot reportedSham acupointsPSQI and PSGImprovements in SWS at PSG and in PSQI score

Painovich et al., 2012 [30]Randomized controlled trialPeri- and postmenopausal women, at least seven VMS/day129/12Three times a week, during 12 weeksBody acupunctureGV-20, PC-6, HT-7, LV-3, LI-4, LI-11, KI-3, SP-6, ST-36, CV-17, CV-6, GV-14, GB-15, GB-18, GB-20, GB-23, GB-34, and KI-3Sham or nonePSQINonsignificant

Kung et al., 2011 [36]CohortPostmenopausal women, insomnia45NADaily before sleep, during four weeksAuricular acupunctureShenMen, kidney, heart, brainstem, and subcortexNAPSQIImprovements in PSQI score, sleep latency, total sleep duration, and sleep efficiency

Borud et al., 2009 [40]Multicentric randomized controlled trialPostmenopausal women, at least seven hot flushes/day13413310 sessions over 12 weeksBody acupuncture (elective additional moxibustion)Individualized and customized treatmentNoneSleep logs and WHQImprovement in total sleep time

Borud et al., 2010 [34]Follow-up on Borud et al., 2009 [40]Postmenopausal women, at least seven hot flushes/day134133NANANANAWHQMaintenance of results, as in Borud et al., 2009 [40]

Avis et al., 2008 [32]Randomized controlled trialPeri- or postmenopausal women, at least four hot flushes/day1918Twice a week, during eight weeksBody acupunctureCV-4, KI-3, SP-6, BL-23, HT-6, KI-7 (possible additional points depending on diagnostic: KI-6, KI-10, GV-4, CV-6, BL-52, LR-3, LR-8, GB-20, BL-18, PC-7, GB-13, GV-20, taiyang, HT-7, HT-8, Yintang, CV-15, BL-15)Sham acupointsWomen's Health Initiative Insomnia Rating ScaleNonsignificant

Huang et al., 2006 [31]Randomized controlled trialPostmenopausal women, at least 7 moderate or severe hot flushes/day1217Nine sessions, during seven weeksBody acupuncture5–7 acupoints from a previously defined listSham acupointsPSQINonsignificant

Hu, 2005 [37]Case report51-y postmenopausal woman1NAThree times a week, duration not clearBody and auricular acupunctureBL-23, BL-15, PC-7, HT-7, Anmian (extra), SP-6, LR-3, KI-3, BL-18, BL-20, GV-20, GV-24, EX-HN 3 Auricular: subcortex, sympathesis, ear-ShenMen, endocrine, ovary, kidney, spleen, and heartNAInsomnia self-reportImprovement

Cohen et al., 2003 [33]Randomized controlled trialPostmenopausal woman, self- identification of menopausal hot flashes89Irregular schedule, total six sessionsBody acupunctureBL-15, BL-23, BL-32, GV-20, HT-7, PC-6, SP-6, SP-9, LI-3Standard treatment, not related to menopause0–3 scale about sleep disorders severityNonsignificant between groups comparison Improvement in within-group comparison

Bijak, 2009 [29]Case report59-y postmenopausal woman1NAOnce a week, ten weeksBody and auricular acupunctureBL-17 (until the 4th session), BL-43 (5th until the 10th session), KI-3, BL-31, HT-3, LI-3, auricular: Jerome's point and sleep point (until the 4th session)NAInsomnia self-reportImprovement

Exp: experimental group; ctrl: control group; -exp: sample size at experimental group; -ctrl: sample size at control group; NA: not applicable; PSQI: Pittsburgh Sleep Quality Index; PSG: Polysomnography; WHQ: Women's Health Questionnaire; SWS: slow wave sleep.