Inhibitory Properties of Aqueous Ethanol Extracts of Propolis on Alpha-Glucosidase

Table 3

Inhibitory kinetics and Ki values of various propolis extracts against baker’s yeast alpha-glucosidase.

Aqueous ethanol extracts of propolis (EEP)	Kinetic mode	Ki (μg/mL)
WEP	Competitive inhibition	10.43 ± 1.41^b
25% EEP	Competitive inhibition	9.85 ± 2.48^b
50% EEP	Mixed inhibition	9.92 ± 0.43^b
75% EEP	Noncompetitive inhibition	15.18 ± 0.58^a
95% EEP	Mixed inhibition	9.65 ± 1.54^b
100% EEP	Mixed inhibition	10.89 ± 2.84^b

Note: Water extracts of propolis were expressed as WEP. Extracts of propolis using 25%, 50%, 75%, 95%, and 100% (in water, v/v) aqueous ethanol solvents were expressed as 25% EEP, 50% EEP, 75% EEP, 95% EEP, and 100% EEP, respectively. The inhibition constant of propolis on alpha-glucosidase was expressed as Ki. Dates are mean ± standard deviation (). Values in the same column followed by the same lower case letter are not significantly different by Duncan’s multiple range test ( < 0.05).