Figure 1: Silymarin accelerates cell cycle from G1 phase to S phase during liver regeneration. Expression protein levels for G1 and S phase checkpoint proteins, cyclin D1, pRb, cyclin E, and E2F in Sham, PHx, and silymarin (Sm) treatment PHx by western blot. (a) At 6 hrs PHx, (b) at 24 hrs PHx, and (c) at 72 hrs PHx. Quantification of densitometry analysis of protein expression levels. All data are presented as means SEM, , , as compared with the corresponding sham group. , , as compared with the corresponding PHx. -Tubulin was used as a loading control for western blotting.