Review Article

A Systematic Overview of Reviews for Complementary and Alternative Therapies in the Treatment of the Fibromyalgia Syndrome

Table 3

Overview of conclusions for investigated therapies from included systematic reviews.

InterventionPositive evidenceNegative evidenceInconclusive

Mind/Body interventions
Mind/Body interventions in general(i) Effects on pain [53]  
(ii) More effective than usual care for some outcomes [63]
Meditation-based interventions(i) Mostly positive results [50]  
(ii) Most studies indicate improvement [64]
Mindfulness-based stress reductionModerate short-term effects on FMS key symptoms [65]
Hypnosis/guided imageryStrong short-term effects on pain [61]
Biofeedback(i) Limited evidence for biofeedback [52]  
(ii) Moderate effects on pain for EMG biofeedback [62]
(i) No positive results [50]  
(ii) No effects of EEG biofeedback [62]
RelaxationLimited evidence [52]
Autogenic trainingNo effects of autogenic training [50]

Exercised-based CAM
Qigong(i) Moderate-to-strong short-term effects on FMS key symptoms [56]  
(ii) Moderate effect on functional disability [57]  
(iii) A positive trend [53]
(i) No positive results [50]  
(ii) No evidence of effects [55]
Too early to draw conclusions [54]
Tai Chi(i) Strong effect on functional disability [57]  
(ii) Moderate effect on sleep quality [55]  
(iii) One study in favor of tai chi [53]
Yoga(i) Significant effects on pain, fatigue, depression, and quality of life [55]  
(ii) Moderate effect on functional disability [57]

Manipulative therapies
Chiropractic interventionsLimited evidence [60](i) No positive evidence [58]  
(ii) Insufficient evidence for benefit [52]
Not enough evidence [53]
Massage(i) Moderate evidence [52]  
(ii) Massage is beneficial for patients with fibromyalgia [59]
Ineffective [53]

Acupuncture
(i) Strong evidence [52]  
(ii) Strong evidence for small short-term effects on pain [67]  
(iii) Low-to-moderate evidence for acupuncture compared to usual care or standard care [66]
(i) Ineffective [53]  
(ii) No evidence for effectiveness [68]
(i) Mixed quality [50]  
(ii) Effectiveness not yet supported, mixed evidence [69]

Balneotherapy/hydrotherapy
(i) Positive evidence [50]  
(ii) Limited evidence [52]  
(iii) Effects on pain [53]  
(iv) Moderate evidence for pain [69]  
(v) Strong evidence [72]  
(vi) Appears efficacious [70]

Phytotherapy
Unclear whether medicinal products or related natural products are effective [73]

Nutritional supplements
Limited evidence for diverse supplements [52]Ineffective [53]

Homeopathy
(i) Positive results [50]  
(ii) Limited evidence [52]  
(iii) Some evidence [51]
(i) Not enough evidence [53]  
(ii) Effectiveness remains unproven [74]