Research Article

Neurosupportive Role of Vanillin, a Natural Phenolic Compound, on Rotenone Induced Neurotoxicity in SH-SY5Y Neuroblastoma Cells

Figure 6

Vanillin protects SH-SY5Y cells against rotenone induced apoptosis. (a) Photomicrograph showing the antiapoptotic effect of vanillin (100 nM) against rotenone at a concentration of 100 nM effective dose. (A) Control, (B) rotenone, (C) vanillin + rotenone, and (D) vanillin. (b) Rotenone (100 nM) treatment induced cell apoptosis compared to control cells; pretreatment with vanillin (100 nM) suppresses these apoptotic features. Values are given as mean ± SD of four independent experiments in each group. compared to control and compared to rotenone group (DMRT).
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