Table 2: Scores of motor symptoms and nonmotor symptoms before and after EA add-on treatment in the D + EA group, and before and after 2 months in the D group.

D + EA groupD group
Before EAAfter EABefore 2 monthsAfter 2 months

Motor symptoms
UPDRS III [points (mean ± SD)]25.6 ± 2.820.6 ± 2.70.00023.3 ± 13.022.5 ± 12.10.061a
 Subitems of UPDRS III
  Tremor [points (mean ± SD)]4.9 ± 4.43.4 ± 3.90.0014.5 ± 3.14.3 ± 2.80.353a
  Rigidity [points (mean ± SD)]4.6 ± 3.43.6 ± 3.2 0.0044.2 ± 4.14.0 ± 3.90.070a
  Bradykinesia [points (mean ± SD)]9.0 ± 6.37.4 ± 5.90.0007.8 ± 5.37.4 ± 5.20.072a
  Gait and postural abnormality [points (mean ± SD)]2.8 ± 1.3 2.7 ± 1.60.788a3.6 ± 2.53.4 ± 2.20.168a
 UPDRS III of different PD clinical phenotypes
  Tremor type [points (mean ± SD)]14.0 ± 6.510.0 ± 3.00.373a9.8 ± 6.89.7 ± 6.70.363a
  Rigidity-bradykinesia type [points (mean ± SD)]17.8 ± 5.013.6 ± 3.90.02721.8 ± 5.719.8 ± 2.20.391a
  Mixed type [points (mean ± SD)]31.3 ± 3.125.8 ± 3.50.00032.0 ± 10.630.5 ± 9.80.062a
 UPDRS III scores of different PD severity
  Mild degree [points (mean ± SD)]20.2 ± 2.614.7 ± 2.00.00016.6 ± 9.115.8 ± 8.30.056a
  Moderate degree [points (mean ± SD)]33.5 ± 3.929.1 ± 4.10.055a33.4 ± 11.531.1 ± 10.10.090a
H-Y Stage (stage, mean ± SD) 2.0 ± 0.71.9 ± 0.70.096a2.1 ± 0.82.0 ± 0.81.000a
Nonmotor symptoms
 PSQI [points, median (quartile)]21.0 (18.0~25.3)20.0 (18.0~22.0)0.01816.5 (13.8~23.0)16.5 (13.3~22.0)0.850b
 HAMD [points, median (quartile)]12.0 (7.0~19.0)12.0 (7.0~18.0)0.0347.5 (5.0~17.8)7.5 (5.0~14.5)0.870b
 HAMA [points, median (quartile)]13.5 (10.0~16.0)12.5 (7.3~14.0)0.235b9.0 (6.3~14.0)8.5 (6.0~13.8)0.694b
 MMSE [points, median (quartile)]29.0 (28.0~30.0)29.0 (28.0~30.0)0.063b28.0 (25.0~29.0)28.0 (25.0~29.0)0.893b
 MoCA [points, median (quartile)]25.0 (22.0~28.0)25.0 (22.0~28.0)0.083b23.5 (17.3~27.0)23.5 (17.3~27.0)0.876b

Values are means ± standard for the Paired -test.
bValues are median (lower quartile, upper quartile) for the Wilcoxon signed-rank test.
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