Table 5: Changes in the levels of neuroinflammatory factors and neurotransmitters in serum in the D + EA and D groups.

D + EA group (after and before EA)D group (after and before 2 months)

Neuroinflammatory factors
 NO [mmol/L, median (quartile)]53.181 (6.421~64.505)80.494 (62.154~107.569)0.003
 IL-1β [pg/mL, median (quartile)]2.083 (−0.938~5.337) 2.525 (−3.358~4.034)0.425
 PGE2 [pg/mL, median (quartile)]1.373 (−35.700~6.699) 1.436 (−2.378~6.738)0.215
 TNF-α [pg/mL, median (quartile)]8.643 (−22.139~62.882) 20.537 (−17.089~52.414)0.773
Neurotransmitters
 NE [μg/mL, median (quartile)]1.234 (0.734~1.512) 1.208 (0.609~1.878)0.808
 Ach [nmol/L, median (quartile)]0.007 (0.002~0.011) 0.008 (0.003~0.015)0.603
 DA [μg/mL, median (quartile)]1.429 (0.518~3.035) 1.795 (1.161~2.683)0.764
 5-HT [μg/mL, median (quartile)]0.077 (−0.294~0.506)0.703 (0.109~0.981)0.055

Values are median (lower quartile, upper quartile) for the Kruskal-Wallis test.
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