Research Article
Xueshuan Xinmaining Tablet Treats Blood Stasis through Regulating the Expression of F13a1, Car1, and Tbxa2r
Table 3
Effect of XXT on the plasma coagulation parameters and platelet aggregation rate in rats (
,
= 10).
| Group | Dose (mg/kg) | Plasma coagulation parameters | Platelet aggregation rate (%) | APTT (s) | PT (INR) | TT (s) | FIB (g/L) |
| NC | — | 21.98 ± 3.44** | 1.40 ± 0.11* | 27.42 ± 2.47** | 1.99 ± 0.13** | 22.89 ± 5.07** |
| Model | — | 16.58 ± 1.61 | 1.29 ± 0.08 | 23.68 ± 2.64 | 4.69 ± 0.40 | 35.72 ± 3.39 |
| XXT | 350 | 16.94 ± 2.48 | 1.35 ± 0.09 | 23.56 ± 2.47 | 4.57 ± 0.38 | 31.84 ± 5.45 | 700 | 18.31 ± 2.00* | 1.39 ± 0.18 | 27.06 ± 3.35* | 4.71 ± 0.42 | 31.06 ± 3.92* | 1400 | 19.52 ± 3.63* | 1.45 ± 0.23* | 27.88 ± 3.26** | 4.54 ± 0.31 | 28.25 ± 5.42** |
| BCN | 800 | 19.03 ± 3.16* | 1.37 ± 0.11 | 26.50 ± 3.07* | 4.68 ± 0.35 | 29.65 ± 5.50** |
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< 0.05, < 0.01 versus the blood stasis model. Normal control (NC).
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