Research Article

Xueshuan Xinmaining Tablet Treats Blood Stasis through Regulating the Expression of F13a1, Car1, and Tbxa2r

Table 3

Effect of XXT on the plasma coagulation parameters and platelet aggregation rate in rats (, = 10).

GroupDose (mg/kg)Plasma coagulation parametersPlatelet aggregation rate (%)
APTT (s)PT (INR)TT (s)FIB (g/L)

NC21.98 ± 3.44**1.40 ± 0.11*27.42 ± 2.47**1.99 ± 0.13**22.89 ± 5.07**

Model16.58 ± 1.611.29 ± 0.0823.68 ± 2.644.69 ± 0.4035.72 ± 3.39

XXT35016.94 ± 2.481.35 ± 0.0923.56 ± 2.47 4.57 ± 0.3831.84 ± 5.45
70018.31 ± 2.00*1.39 ± 0.1827.06 ± 3.35*4.71 ± 0.4231.06 ± 3.92*
140019.52 ± 3.63*1.45 ± 0.23*27.88 ± 3.26**4.54 ± 0.3128.25 ± 5.42**

BCN80019.03 ± 3.16*1.37 ± 0.11 26.50 ± 3.07*4.68 ± 0.3529.65 ± 5.50**

< 0.05, < 0.01 versus the blood stasis model. Normal control (NC).