[Retracted] Allium cepa L. and Quercetin Inhibit RANKL/Porphyromonas gingivalis LPS-Induced Osteoclastogenesis by Downregulating NF-κB Signaling Pathway

Figure 3

RANKL/PgLPS-induced RAW 264.7 cells were affected by AcE or Qt during osteoclastogenesis. (a) TRAP staining by brightfield microscope showed differentiated osteoclasts in the presence of AcE or Qt after 5 days. The arrows show decreased size of osteoclasts; TRAP-stained, fixed cultures were for number of nuclei per cell in two different groups: (b) 2–5 small and (c) +10 large nuclei per cell. (d) The acid phosphatase activity of the osteoclasts was decreased in all AcE and Qt concentrations tested: , , and when compared with Ctrl group according to the ANOVA and Tukey tests. Results were expressed in mean ± SD of three independent experiments.

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