Review Article

Effects of Whole-Body Vibration Therapy in Patients with Fibromyalgia: A Systematic Literature Review

Table 5

Outcome measures.

AuthorsReferenceInstrumentOutcome measureCG baselineCG after treatmentEG baselineEG after treatmentTreatment effectReported effect

Alentorn-Geli et al. [27]ELISAIGF-1NRNRNRNRNR=
[29]FIQFunctional capacityNRNRNRNRNRΔ
100 mm VASPainNRNRNRNRNRΔ ↑
FatigueNRNRNRNRNRΔ ↑
StiffnessNRNRNRNRNR
DepressionNRNRNRNRNR=

Gusi et al. [31]FIQFunctional capacity53.6 ± 12.3  
55.27 ± 12.73*
57.5 ± 11.2  
59.13 ± 11.71*
59.3 ± 9.8  
56.89 ± 10.38*
56.7 ± 11.1  
55.40 ± 11.41*
−6.42  
−5.35*
↑  
15D questionnaireQuality of life0.65 ± 0.1NR0.63 ± 0.1NRNR=
[30]Biodex Balance SystemDynamic balance1.47 ± 0.55  
1.40 ± 0.55*
1.51  
1.43*
1.49 ± 0.67  
1.59 ± 0.73*
0.85  
1.02*
−0.69  
−0.60*
↑  
[32]Biodex Balance SystemSB overall SI (°)1.36 ± 0.501.40 ± 0.501.53 ± 0.560.88 ± 0.41−0.65
SB anteroposterior SI (°)0.80 ± 0.290.96 ± 0.471.05 ± 0.490.56 ± 0.31−0.64
SB mediolateral SI (°)0.94 ± 0.370.83 ± 0.260.88 ± 0.370.55 ± 0.22−0.19=

Sañudo et al. [34]T-Force Dynamic Measurement SystemKnee extensor strength207.4 ± 16.5202.6 ± 13.6208.2 ± 16.7210.7 ± 18.17.3=
Biodex Balance SystemOE overall SI7.50 ± 3.076.47 ± 2.986.63 ± 3.235.5 ± 2.67−0.1=
OE mean deflection6.25 ± 2.935.63 ± 2.865.52 ± 2.874.66 ± 2.55−0.2=
OE anteroposterior SI5.42 ± 2.135.33 ± 2.684.97 ± 2.454.76 ± 2.81−0.1=
OE anteroposterior mean deflection2.93 ± 1.373.48 ± 2.642.90 ± 1.793.60 ± 2.810.2=
OE mediolateral SI5.07 ± 2.573.35 ± 1.974.34 ± 2.322.49 ± 1.09−0.1
OE mediolateral mean deflection1.61 ± 1.181.23 ± 0.931.28 ± 1.041.17 ± 0.750.3=
CE overall SI11.67 ± 2.4111.37 ± 2.3211.9 ± 2.1610.7 ± 2.64−0.9=
CE mean deflection10.35 ± 2.259.90 ± 2.3010.51 ± 2.149.26 ± 2.57−0.8=
CE anteroposterior SI8.97 ± 1.888.86 ± 2.409.37 ± 2.258.75 ± 2.93−0.5=
CE anteroposterior mean deflection4.12 ± 2.413.74 ± 2.284.25 ± 2.365.01 ± 3.711.1=
CE mediolateral SI7.37 ± 2.306.25 ± 2.057.47 ± 1.285.56 ± 1.38−0.8
CE mediolateral mean deflection2.55 ± 1.492.01 ± 1.332.75 ± 1.312.01 ± 1.34−0.2=
[33]FIQFunctional capacity56.66 ± 11.5849.81 ± 14.8748.89 ± 12.0843.79 ± 12.311.7Δ#
SF-36Quality of life33.58 ± 12.1042.51 ± 11.3044.16 ± 18.8854.00 ± 15.830.9Δ↑#
T-Force SystemMaximum power of knee extensor muscles80.92 ± 24.1785.01 ± 19.7381.29 ± 28.3487.05 ± 19.721.7=
Number of repetitions22.08 ± 9.2124.71 ± 6.2623.75 ± 7.8728.71 ± 5.252.3Δ
Muscular fatigue index0.91 ± 0.140.96 ± 0.050.90 ± 0.060.97 ± 0.170.0=

Sañudo et al. [28]Biodex Stability SystemOE overall SI5.53 (1.49)6.10 (1.40)7.02 (3.66)5.75 (2.51)−1.84=
OE mean deflection4.58 (1.32)4.99 (1.16)5.85 (3.18)4.67 (2.09)−1.59=
OE anteroposterior SI4.46 (1.36)5.03 (1.21)5.36 (2.90)4.92 (2.18)−1.01=
OE anteroposterior mean deflection2.18 (1.67)2.40 (1.08)2.47 (2.24)2.48 (1.29)−0.21=
OE mediolateral SI3.35 (1.17)3.83 (1.37)4.54 (2.56)2.94 (1.44)−2.08Δ↑
OE mediolateral mean deflection1.23 (1.66)0.76 (0.19)2.28 (1.08)1.31 (0.21)−0.5
CE overall SI9.31 (1.83)8.89 (1.95)9.91 (3.64)9.10 (2.99)−0.39=
CE mean deflection7.90 (1.77)7.63 (1.80)8.43 (3.55)7.76 (2.83)−0.4=
CE anteroposterior SI7.31 (1.93)7.30 (1.84)7.68 (2.58)7.32 (2.47)−0.37=
CE anteroposterior mean deflection3.21 (2.66)3.87 (2.38)1.90 (2.01)3.18 (2.27)0.62=
CE mediolateral SI5.81 (1.49)5.21 (1.21)6.39 (2.86)5.48 (2.03)−0.31Δ
CE mediolateral mean deflection1.62 (1.02)0.95 (0.84)1.09 (0.87)1.80 (1.02)1.38=
T-Force SystemNumber of repetitions23.72 (7.98)23.50 (6.63)30.85 (8.90)31.14 (7.18)0.51=

CG: control group; EG: exercise group; NR: not reported; ELISA: enzyme-linked immunosorbent assay; IGF-1: serum insulin-like growth factor-1; FIQ: fibromyalgia impact questionnaire; SB: static balance; VAS: visual analogue scale; OE: open eyes; CE: closed eyes; SI: stability index; =: no significant difference relative to baseline and/or the control group; : statistically significant improvement in the WBV group relative to the control group; Δ: statistically significant improvement in the WBV group relative to baseline; #: statistically significant improvement in the control group relative to baseline.
*Intention-to-treat analysis.