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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 748041, 8 pages
Research Article

The Effects of Panax ginseng and Panax quinquefolius on Thermoregulation in Animal Models

1Department of Audiology, Nambu University, Gwangju 506-824, Republic of Korea
2Department of Oriental Medicinal Materials & Processing, College of Life Sciences, Kyung Hee University, Global Campus, Gyeonggi 446-701, Republic of Korea
3Graduate School of Biotechnology, Kyung Hee University, Global Campus, Gyeonggi 446-701, Republic of Korea

Received 1 August 2014; Revised 8 January 2015; Accepted 15 January 2015

Academic Editor: I-Min Liu

Copyright © 2015 Bin Na Hong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We devised a study using animal models of hyperthermia and hypothermia and also attempted to accurately assess the effects of Panax ginseng (PG) and Panax quinquefolius (PQ) on body temperature using these models. In addition, we investigated the effects of PG and PQ in our animal models in high and low temperature environments. The results of our experiments show that mice with normothermia, hyperthermia, and hypothermia maintained their body temperatures after a certain period in accordance with the condition of each animal model. In our experiments of body temperature change in models of normal, low, or high room temperature, the hyperthermic model did not show any body temperature change in either the PG- or PQ-administered group. In the normal and low room temperature models, the group administered PG maintained body temperature, while the body temperature of the PQ-administered group was lower than or similar to that of the control group. In conclusion, the fact that PG increases body temperature could not be verified until now. We also showed that the effect of maintaining body temperature in the PG-administered group was superior in a hypothermia-prone low temperature environment.