Hypocholesterolemic and Antiatherosclerotic Potential of Basella alba Leaf Extract in Hypercholesterolemia-Induced Rabbits

Table 5

Thickness of intima, media, and intima/media ratio of experimental rabbits at week 12.

Groups	Intima thickness (µm)	Media thickness (µm)	Intima/media
G1	1045.439 ± 80.26	3350.768 ± 213.40	0.312 ± 0.039
G2	4203.296 ± 160.96	6004.708 ± 102.28	0.700 ± 0.023
G3	1585.270 ± 111.40	3809.198 ± 160.44	0.416 ± 0.035
G4	1786.301 ± 104.59	3978.398 ± 85.94	0.449 ± 0.019
G5	1720.678 ± 152.25	4058.203 ± 181.25	0.424 ± 0.033

G1: normal control, G2: hypercholesterolemic control, G3: simvastatin-treated (10 mg/kg), G4: B. alba extract-treated (100 mg/kg), and G5: B. alba extract-treated (200 mg/kg). All data are presented as the mean ± SD ( for each group). One-way ANOVA was performed followed by Dunnett’s post hoc test for multiple comparisons. Within a column, values sharing the same superscript letters are not significantly different from each other ( < 0.05).