Rapid Antidepressant Activity of Ethanol Extract of Gardenia jasminoides Ellis Is Associated with Upregulation of BDNF Expression in the Hippocampus

Figure 4

Rapid antidepressant effects of GJ in the learned helplessness paradigm. Learned helplessness was quantified as number of escape failures in an active avoidance test. Mice received inescapable shock training for two days prior to a 30-trial active avoidance test. ANOVA, F_(4,39) = 60.793, , and /group, compared to control, ^### compared to vehicle, LSD post hoc tests.