Evidence-Based Complementary and Alternative Medicine / 2015 / Article / Tab 1

Research Article

Protective Effects of N-Acetyl-L-Cysteine in Human Oligodendrocyte Progenitor Cells and Restoration of Motor Function in Neonatal Rats with Hypoxic-Ischemic Encephalopathy

Table 1

Statistical analysis of the apoptosis-related molecules from Figures 2 and 3.

Treatment (mM)Annexin V positivity (%)Bcl2 (relative to GAPDH)Bad (relative to GAPDH)p-ERK (relative to GAPDH)

Vehicle3.6 ± 2.7a0.28 ± 0.13a0.001 ± 0.001a0.097 ± 0.015a
KCN (5.0)56.8 ± 4.8b0.11 ± 0.06b0.312 ± 0.124b0.065 ± 0.011b
+vitamin C (0.15)98.6 ± 7.4c0.21 ± 0.11ab0.282 ± 0.152b0.068 ± 0.082ab
+NAC (0.5)42.7 ± 3.4d0.37 ± 0.14ac0.521 ± 0.206b0.124 ± 0.113a
+NAC (1.0)32.3 ± 5.1df0.68 ± 0.20d0.341 ± 0.093b0.156 ± 0.108c
+NAC (2.5)26.1 ± 2.8e0.91 ± 0.26d0.238 ± 0.062b0.202 ± 0.077c
+NAC (5.0)31.3 ± 4.2ef0.82 ± 0.22d0.110 ± 0.046c0.235 ± 0.086c

Values () in the same column with different superscript letters represent a significant difference, P < 0.05.

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