Hypoglycemic Effect of Ethanol and Ethyl Acetate Extract of Phellinus baumii Fruiting Body in Streptozotocin-Induced Diabetic Mice
Table 1
Effect of P. baumii on the body weight gain of diabetes mice.
Group
Dose (mg/kg)
Animal numbera (piece)
First day
Fifth day
Seventh dayb
Ninth dayc
Thirteenth day
Fourteenth day
Control
—
10
21.1 ± 1.7
26.2 ± 1.2
28.8 ± 1.6
30.7 ± 2.1
33.7 ± 2.3
34.9 ± 2.4
Model
—
9
20.3 ± 1.5
20.2 ± 1.5##
19.6 ± 1.7##
19.7 ± 1.4##
19.0 ± 1.9##
18.8 ± 1.6##
AcOEt extract
100
9
20.3 ± 1.6
20.1 ± 1.9
20.3 ± 2.3
20.1 ± 2.2
20.3 ± 2.6
21.1 ± 2.8
200
10
20.5 ± 1.7
20.8 ± 1.6
20.6 ± 2.4
20.1 ± 2.1
21.1 ± 2.3
22.2 ± 2.0
400
9
20.4 ± 1.4
19.9 ± 1.7
20.3 ± 2.5
20.2 ± 2.1
20.2 ± 2.1
21.3 ± 2.2
EtOH extract
100
10
20.2 ± 2.0
20.1 ± 2.5
19.2 ± 2.4
19.6 ± 2.4
19.5 ± 1.8
19.9 ± 2.2
200
9
20.4 ± 1.5
20.4 ± 2.1
20.3 ± 2.0
20.0 ± 1.9
19.7 ± 2.1
20.2 ± 2.3
400
10
20.3 ± 1.9
20.4 ± 2.3
20.0 ± 2.2
19.9 ± 1.5
20.3 ± 2.8
20.6 ± 2.2
Metformin
160
10
20.4 ± 1.7
20.3 ± 2.1
20.8 ± 1.6
20.7 ± 1.6
20.2 ± 1.2
22.1 ± 1.5
versus normal control group; , versus model control group. aMice number of each group at fourteenth day. bMice number of each group was ten at seventh day. cMice numbers of 100 mg/kg AcOEt extract group and mode group were nine, and number of the other group was ten at ninth day.
