Research Article

Different Proportions of Huangqi (Radix Astragali Mongolici) and Honghua (Flos Carthami) Injection on -Glucosidase and -Amylase Activities

Table 2

Inhibitory effect of Huangqi (Radix Astragali Mongolici) injection, Honghua (Flos Carthami) injection, and different proportions on yeast -glucosidase activity ().

GroupConcentration
(µg/mL)
Percentage of inhibition
(%)
IC50
(µg/mL)

Acarbose2.570.2 ± 3.21.8 ± 0.4
1.334.0 ± 2.7
0.624.4 ± 1.7
0.312.9 ± 1.2

Huangqi injection200054.1 ± 5.61686 ± 810a
150043.6 ± 3.7
75038.1 ± 2.6
3759.7 ± 1.1

Honghua injection12589.8 ± 5.632.8 ± 5.7ab
62.566.9 ± 5.1
31.346.6 ± 3.7
15.622.8 ± 3.1

Different proportions
 20 : 125067.5 ± 5.7122.6 ± 21.4ab
12549.9 ± 5.1
62.529.1 ± 3.1
31.327.3 ± 2.9
 10 : 125082.0 ± 7.653.8 ± 5.5abc
12567.8 ± 5.3
62.557.3 ± 5.5
31.334.8 ± 3.3
 5 : 125088.1 ± 9.155.5 ± 7.2abc
12577.5 ± 6.9
62.548.8 ± 4.1
31.335.3 ± 2.1
 2 : 125085.7 ± 8.152.4 ± 11.6abc
12566.8 ± 6.1
62.556.9 ± 6.1
31.333.2 ± 3.0

Notes: , compared with acarbose control. , Honghua injection and different proportions compared with Huangqi injection. , proportions 10 : 1, 5 : 1, and 2 : 1 compared with 20 : 1. IC50: half maximal (50%) inhibitory concentration on yeast -glucosidase activity.