Bioactive Polyphenols from the Methanol Extract of Cnicus arvensis (L.) Roth Demonstrated Antinociceptive and Central Nervous System Depressant Activities in Mice

Table 3

Effects of Cnicus arvensis extract on acetic acid induced writhing in mice.

Animal group	Treatment	Writhing (mean ± SEM)	% inhibition
Group I	1% tween solution in water	30.5 ± 0.43	0
Group II	Diclofenac Na (25 mg/kg bd. wt.)	7.67 ± 1.13^*	74.86
Group III	Plant extract (100 mg/kg bd. wt.)	17.33 ± 3.64^*	43.17
Group IV	Plant extract (200 mg/kg bd. wt.)	1.50 ± 0.76^*	95.08

bd. wt. = body weight; SEM = standard error of mean; ; ^*.