Bioactive Polyphenols from the Methanol Extract of Cnicus arvensis (L.) Roth Demonstrated Antinociceptive and Central Nervous System Depressant Activities in Mice
Table 5
Effects of Cnicus arvensis extract on open field test in mice.
Groups
Responses at
min 0
min 30
min 60
min 90
min 120
Control
115.67 ± 2.81
115.17 ± 1.20
110.50 ± 0.99
98.67 ± 1.50
105.00 ± 1.57
Positive control
105.67 ± 2.01*
73.67 ± 3.64*
51.17 ± 1.40*
24.50 ± 2.80*
13.17 ± 1.25*
Plant extract of 150 mg/kg bd. wt.
101.5 ± 4.93
128.67 ± 8.62
75.00 ± 8.73*
30.00 ± 5.59*
33.00 ± 6.76*
Plant extract of 300 mg/kg bd. wt.
206.5 ± 9.79*
159.17 ± 2.80*
105.50 ± 3.96*
101.50 ± 3.27*
74.17 ± 6.76*
bd. wt. = body weight; values are mean ± SEM; ; *.
