Evidence-Based Complementary and Alternative Medicine / 2015 / Article / Fig 1

Research Article

Protective Effect of Triptolide against Glomerular Mesangial Cell Proliferation and Glomerular Fibrosis in Rats Involves the TGF-β1/Smad Signaling Pathway

Figure 1

The effect of triptolide on the TGF-β1-induced RMC proliferation. Triptolide inhibited the TGF-β1-induced proliferation of mesangial cell. The triptolide effect enhanced gradually over a period of 48 h reaching its peak at 48 h and eventually decreasing after 48 h. When the concentration of the triptolide was gradually increased from 0.4 to 10 μg/L, the efficiency of the drug simultaneously increased , .