The Protective Effects of Curcumin on Obesity-Related Glomerulopathy Are Associated with Inhibition of Wnt/β-Catenin Signaling Activation in Podocytes

Figure 3

Effects of curcumin on body weight, Lee’s index, visceral fat index, serum cholesterol, and blood glucose of ORG mice. (a) Average body weight of mice in model group and curcumin group was significantly higher than that in control group at the 8th week; it was significantly lighter in curcumin group than that in model group at the 12th week. versus control group at 8th week, versus model group itself at 8th week, and versus model group at 12th week. (b), (c), and (d) Average Lee’s index, visceral adiposity index, and serum cholesterol levels were significantly increased in mice of model group and curcumin group compared with control group, and the former two parameters were significantly reduced in curcumin group compared with model group at the 12th week. versus control group, versus control group, and versus model group. (e) Average levels of blood glucose in three groups had no significant difference at the 12th week. Values are represented as mean ± SD ().

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