Review Article
Effectiveness of Acupuncture for Primary Ovarian Insufficiency: A Systematic Review and Meta-Analysis
Table 2
Level of evidence (GRADE).
| | Outcomes | Number of participants (number of studies) | Illustrative comparative risks (95% CI) | Level of evidence |
| | FSH | 521
(6 studies) | The mean FSH in acupuncture groups was 9.26 lower (13.11 to 5.41 lower) | Low
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| | Resumption of menstruation | 614
(8 studies) | Acupuncture group: 918 per 1000 (873 to 948)
Control group: 907 per 1000 (857 to 940) | Low
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| | Estradiol (E2) | 479
(6 studies) | The mean E2 in the acupuncture group was 31.51 higher (6.06 to 56.95 higher) | Very low
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| | LH | 278
(4 studies) | The mean LH in the acupuncture groups was 5.34 lower (13.02 lower to 2.34 higher) | Low
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| | Symptoms (Kupperman index) | 121
(2 studies) | The mean symptom score in the acupuncture group ranged from 11.22 to 12.1 higher. | Very low
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