Research Article

Chronic Treatment with a Water-Soluble Extract from the Culture Medium of Ganoderma lucidum Mycelia Prevents Apoptosis and Necroptosis in Hypoxia/Ischemia-Induced Injury of Type 2 Diabetic Mouse Brain

Figure 6

Effects of chronic pretreatment with MAK (1 g/kg) on the expression of necroptotic factor gene expression after H/I. Expression levels of RIP1 (a) and RIP3 (b) mRNA at 6 (after 6 h) or 24 h (after 24 h) of reoxygenation after H/I in the penumbral cortex from the mice in each group, determined by real-time RT-PCR analysis.; in each group. , 0.001. compared with the H/I-treated control group.