Research Article
Fallopia japonica, a Natural Modulator, Can Overcome Multidrug Resistance in Cancer Cells
Table 1
Cytotoxicity (IC50 values µg/mL) of methanolic extracts from TCM plants in Caco-2, HepG-2, and HeLa cells.
| | Plant Latin name (family) | IC50 values | | Caco-2 | HepG-2 | HeLa |
| | Areca catechu (Arecaceae) | 1393.74 ± 120.34 | 308.66 ± 39.75 | 414.29 ± 72.72 | | Cassia tora (Fabaceae) | 1520.01 ± 123.43 | 1074.56 ± 110.70 | 670.94 ± 40.63 | | Chrysanthemum indicum (Asteraceae) | 965.23 ± 90.87 | 880.86 ± 61.35 | 355.75 ± 16.81 | | Cymbopogon distans (Poaceae) | 592.62 ± 15.56 | 410.52 ± 40.19 | 98.85 ± 9.02 | | Cynanchum paniculatum (Apocynaceae) | 2590.48 ± 290.02 | 2167.54 ± 199.84 | 500.50 ± 57.65 | | Desmodium styracifolium (Fabaceae) | 998.54 ± 47.89 | 469.31 ± 17.03 | 324.39 ± 34.68 | | Kadsura longipedunculata (Schisandraceae) | 1439.96 ± 66.47 | 368.54 ± 30.09 | 86.11 ± 3.21 | | Mentha haplocalyx (Lamiaceae) | 1170.12 ± 40.11 | 997.45 ± 56.89 | 375.06 ± 50.61 | | Ophioglossum vulgatum (Ophioglossaceae) | 1584.14 ± 38.08 | 1102.23 ± 76.39 | 469.06 ± 54.73 | | Paris polyphylla (Melanthiaceae) | 53.87 ± 5.67 | 48.31 ± 4.43 | 35.04 ± 6.45 | | Patrinia scabiosaefolia (Valerianaceae) | 1488.25 ± 68.12 | 413.30 ± 93.83 | 159.41 ± 8.56 | | Fallopia japonica (Polygonaceae) | 630.98 ± 40.21 | 198.80 ± 16.80 | 317.37 ± 22.27 | | Sanguisorba officinalis (Rosaceae) | 1380.69 ± 60.77 | 169.49 ± 17.82 | 158.53 ± 13.25 | | Saposhnikovia divaricata (Apiaceae) | 2420.03 ± 210.54 | 980.34 ± 89.76 | 368.20 ± 19.88 | | Taxillus chinensis (Loranthaceae) | 1310.34 ± 31.21 | 1123.65 ± 52.43 | 1213.42 ± 21.47 | | Viola yezoensis (Violaceae) | 520.23 ± 70.43 | 345.23 ± 34.23 | 297.53 ± 19.99 |
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