Yokukansan Improves Mechanical Allodynia through the Regulation of Interleukin-6 Expression in the Spinal Cord in Mice with Neuropathic Pain

<div>Typical example of the distribution of interleukin- (IL-) 6 in the dorsal horn of the lumbar spinal cord in mice with mechanical allodynia induced by partial sciatic nerve ligation (PSL). The sections of the lumbar spinal cord are double-immunostained with IL-6 (green) and glial fibrillary acidic protein (GFAP) ((a) red), ionized calcium-binding adaptor molecule 1 (Iba-1) ((b) red), or NeuN ((c) red). Scale bars = 10 <i>μ</i>m.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 5

Figure 5: Yokukansan Improves Mechanical Allodynia through the Regulation of Interleukin-6 Expression in the Spinal Cord in Mice with Neuropathic Pain 

Figure 5 | Yokukansan Improves Mechanical Allodynia through the Regulation of Interleukin-6 Expression in the Spinal Cord in Mice with Neuropathic Pain 