Evidence-Based Complementary and Alternative Medicine / 2015 / Article / Tab 2

Research Article

Rikkunshito Ameliorates Cancer Cachexia Partly through Elevation of Glucarate in Plasma

Table 2

Metabolites significantly changed in plasma of tumor-bearing and normal rats in response to RKT treatment.

Compound nameTumorNormal
Fold
change
valueFold
change
value

Glucarate1.58<0.00011.310.026
Alanine1.45<0.00010.970.66
Lactic acid1.57<0.00011.050.58
Adipic acid1.30<0.00011.050.54
Fructose1.660.00010.870.074
Aspartic acid1.220.00021.010.84
Pyruvate + oxalacetic acid1.310.00121.100.23
Oxalate1.260.00191.640.23
Tryptophan1.260.00590.860.14
Arabitol1.480.0101.470.0049
Fumaric acid1.190.0171.040.70
Lysine1.130.0171.070.15
Proline1.360.0190.960.75
Phenylalanine1.190.0240.990.94
N-Acetyl-L-glutamate0.690.0250.940.47
Phosphate1.160.0361.110.085
Glucono-1,4-lactone1.110.0371.130.096
Allantoin1.140.0411.030.58
Lauric acid0.850.0420.69<0.0001
Cysteine + cystine0.830.0430.990.91
4-Hydroxyphenylacetic acid1.220.0441.030.79
Glucose1.160.0441.110.083
Urea1.160.0481.100.11

Each value represents the fold induction of the peak intensity in RKT-treated rats () against that of vehicle-treated controls (). values were calculated by unpaired Student’s -test.

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