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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 873954, 6 pages
http://dx.doi.org/10.1155/2015/873954
Research Article

Evaluation of Sedative and Hypnotic Activity of Ethanolic Extract of Scoparia dulcis Linn.

1College of Pharmacy, Dongguk University, Goyang 410-820, Republic of Korea
2Department of Pharmacy, Stamford University Bangladesh, 51 Siddeswari Road, Dhaka 1217, Bangladesh

Received 24 December 2014; Accepted 5 March 2015

Academic Editor: Wagner Vilegas

Copyright © 2015 Md. Moniruzzaman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. G. Katzung, S. B. Masters, and A. J. Trevor, Basic and Clinical Pharmacology, McGraw-Hill, New York, NY, USA, 11th edition, 2009.
  2. K. Dhawan, S. Dhawan, and S. Chhabra, “Attenuation of benzodiazepine dependence in mice by a tri-substituted benzoflavone moiety of Passiflora incarnata Linneaus: a non-habit forming anxiolytic,” Journal of Pharmacy & Pharmaceutical Sciences, vol. 6, no. 2, pp. 215–222, 2003. View at Google Scholar · View at Scopus
  3. S. M. F. Freire, J. A. S. Emim, A. J. Lapa, C. Souccar, and L. M. B. Torres, “Analgesic and antiinflammatory properties of Scoparia dulcis L. extracts and glutinol in rodents,” Phytotherapy Research, vol. 7, no. 6, pp. 408–414, 1993. View at Publisher · View at Google Scholar · View at Scopus
  4. A. H. M. Zulfiker, M. M. Mahbubur Rahman, M. Kamal Hossain, K. Hamid, M. E. H. Mazumder, and M. Sohel Rana, “In vivo analgesic activity of ethanolic extracts of two medicinal plants—Scoparia dulcis L. And Ficus racemosa Linn,” Biology and Medicine, vol. 2, no. 2, pp. 42–48, 2010. View at Google Scholar · View at Scopus
  5. M. A. Adaikpoh, N. E. J. Orhue, and I. Igbe, “The protective role of Scoparia dulcis on tissue antioxidant defense system of rats exposed to cadmium,” African Journal of Biotechnology, vol. 6, no. 10, pp. 1192–1196, 2007. View at Google Scholar · View at Scopus
  6. L. Pari and M. Latha, “Protective role of Scoparia dulcis plant extract on brain antioxidant status and lipidperoxidation in STZ diabetic male Wistar rats,” BMC Complementary and Alternative Medicine, vol. 4, article 16, 2004. View at Publisher · View at Google Scholar · View at Scopus
  7. N. E. J. Orhue and E. A. C. Nwanze, “Anti anaemic properties of Scoparia dulcis in Trypanosoma brucei infected rabbits,” African Journal of Biochemistry Research, vol. 3, no. 5, pp. 245–249, 2009. View at Google Scholar
  8. M. Latha, L. Pari, S. Sitasawad, and R. Bhonde, “Insulin-secretagogue activity and cytoprotective role of the traditional antidiabetic plant Scoparia dulcis (Sweet broomweed),” Life Sciences, vol. 75, no. 16, pp. 2003–2014, 2004. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Latha, K. M. Ramkumar, L. Pari, P. N. Damodaran, V. Rajeshkannan, and T. Suresh, “Phytochemical and antimicrobial study of an antidiabetic plant: Scoparia dulcis L,” Journal of Medicinal Food, vol. 9, no. 3, pp. 391–394, 2006. View at Publisher · View at Google Scholar · View at Scopus
  10. T. Hayashi, M. Kawasaki, Y. Miwa, T. Taga, and N. Morita, “Antiviral agents of plant origin. III. Scopadulin, a novel tetracyclic diterpene from Scoparia dulcis L.,” Chemical and Pharmaceutical Bulletin, vol. 38, no. 4, pp. 945–947, 1990. View at Publisher · View at Google Scholar · View at Scopus
  11. A. Ghani, Medicinal Plant of Bangladesh with Chemical Constituents and Uses, Asiatic Society of Bangladesh, Dhaka, Bangladesh, 2nd edition, 2003.
  12. C. I. B. Walker, G. Trevisan, M. F. Rossato et al., “Antinociceptive activity of Mirabilis jalapa in mice,” Journal of Ethnopharmacology, vol. 120, no. 2, pp. 169–175, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Takagi, M. Watanabe, and H. Saito, “Studies of the spontaneous movement of animals by the hole cross test; effect of 2-dimethyl-aminoethanol and its acyl esters on the central nervous system,” The Japanese Journal of Pharmacology, vol. 21, no. 6, pp. 797–810, 1971. View at Publisher · View at Google Scholar · View at Scopus
  14. B. D. Gupta, P. C. Dandiya, and M. L. Gupta, “A psycho-pharmacological analysis of behaviour in rats,” The Japanese Journal of Pharmacology, vol. 21, no. 3, pp. 293–298, 1971. View at Publisher · View at Google Scholar · View at Scopus
  15. Y. Ozturk, S. Aydine, K. H. C. Baser, and H. Berberoglu, “Effects of Hypericum perforatum L. and Hypericum calycinum L. extracts on the central nervous system in mice,” Phytomedicine, vol. 3, no. 2, pp. 139–146, 1996. View at Publisher · View at Google Scholar · View at Scopus
  16. H. Fujimori and D. P. Cobb, “Central nervous system depressant activity of MA1337, 3-[3-(4-m-chlorophenyl-1-piperazyl)propyl]-2,4(1H,3H) quinozolinedine hydrochloride,” Journal of Pharmacology and Experimental Therapeutic, vol. 148, pp. 151–157, 1965. View at Google Scholar · View at Scopus
  17. R. A. Turner, “Anticonvulsant,” in Screening Methods in Pharmacology, p. 158, Academic Press, New York, NY, USA, 1st edition, 1965. View at Google Scholar
  18. L. Prut and C. Belzung, “The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review,” European Journal of Pharmacology, vol. 463, no. 1–3, pp. 3–33, 2003. View at Publisher · View at Google Scholar · View at Scopus
  19. H. Takeda, M. Tsuji, and T. Matsumiya, “Changes in head-dipping behavior in the hole-board test reflect the anxiogenic and/or anxiolytic state in mice,” European Journal of Pharmacology, vol. 350, no. 1, pp. 21–29, 1998. View at Publisher · View at Google Scholar · View at Scopus
  20. S. E. File and S. Pellow, “Intrinsic actions of the benzodiazepine receptor antagonist, Ro 15-1788,” Psychopharmacology, vol. 88, no. 1, pp. 1–11, 1986. View at Publisher · View at Google Scholar · View at Scopus
  21. H. Viola, C. Wasowski, M. L. De Stein et al., “Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects,” Planta Medica, vol. 61, no. 3, pp. 213–216, 1995. View at Publisher · View at Google Scholar · View at Scopus
  22. C. López-Rubalcava, R. Hen, and S. L. Cruz, “Anxiolytic-like actions of toluene in the burying behavior and plus-maze tests: differences in sensitivity between 5-HT(1B) knockout and wild-type mice,” Behavioural Brain Research, vol. 115, no. 1, pp. 85–94, 2000. View at Publisher · View at Google Scholar · View at Scopus
  23. S. Farkas, P. Berzsenyi, E. Kárpáti, P. Kocsis, and I. Tarnawa, “Simple pharmacological test battery to assess efficacy and side effect profile of centrally acting muscle relaxant drugs,” Journal of Pharmacological and Toxicological Methods, vol. 52, no. 2, pp. 264–273, 2005. View at Publisher · View at Google Scholar · View at Scopus
  24. R. Estrada-Reyes, M. Martínez-Vázquez, A. Gallegos-Solís, G. Heinze, and J. Moreno, “Depressant effects of Clinopodium mexicanum Benth. Govaerts (Lamiaceae) on the central nervous system,” Journal of Ethnopharmacology, vol. 130, no. 1, pp. 1–8, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. S. Fernández, C. Wasowski, A. C. Paladini, and M. Marder, “Sedative and sleep-enhancing properties of linarin, a flavonoid-isolated from Valeriana officinalis,” Pharmacology Biochemistry and Behavior, vol. 77, no. 2, pp. 399–404, 2004. View at Publisher · View at Google Scholar · View at Scopus
  26. P. Kahnberg, E. Lager, C. Rosenberg et al., “Refinement and evaluation of a pharmacophore model for flavone derivatives binding to the benzodiazepine site of the GABAA receptor,” Journal of Medicinal Chemistry, vol. 45, no. 19, pp. 4188–4201, 2002. View at Publisher · View at Google Scholar · View at Scopus
  27. E. Trofimiuk, A. Walesiuk, and J. J. Braszko, “St John's wort (Hypericum perforatum) diminishes cognitive impairment caused by the chronic restraint stress in rats,” Pharmacological Research, vol. 51, no. 3, pp. 239–246, 2005. View at Publisher · View at Google Scholar · View at Scopus
  28. R. Awad, F. Ahmed, N. Bourbonnais-Spear et al., “Ethnopharmacology of Q'eqchi' Maya antiepileptic and anxiolytic plants: effects on the GABAergic system,” Journal of Ethnopharmacology, vol. 125, no. 2, pp. 257–264, 2009. View at Publisher · View at Google Scholar · View at Scopus
  29. R. Estrada-Reyes, C. López-Rubalcava, L. Rocha, G. Heinze, A. R. González Esquinca, and M. Martínez-Vázquez, “Anxiolytic-like and sedative actions of Rollinia mucosa: possible involvement of the GABA/benzodiazepine receptor complex,” Pharmaceutical Biology, vol. 48, no. 1, pp. 70–75, 2010. View at Publisher · View at Google Scholar · View at Scopus
  30. R. N. Takahashi, T. C. M. De Lima, and G. S. Morato, “Pharmacological actions of tannic acid; II. Evaluation of CNS activity in animals,” Planta Medica, vol. 4, pp. 272–275, 1986. View at Google Scholar · View at Scopus