Study ID Adverse reaction Risk of bias Follow-up Random method Overall effect OR (95% CI) TCM syndrome effect Hp OR (95% CI) Gastroscope OR (95% CI) Pathology OR (95% CI) Overall effect value Chen and Lai 2013 [7 ] Not mentioned Low Not mentioned Not mentioned 3.08 (1.10, 8.62) OR 6.67 (1.41, 31.59) 0.03 Fu et al. 2013 [8 ] Not found Low Not mentioned Random number table 5.21 (1.28, 21.24) MD −5.85 (−7.71, −3.99) 0.02 Zhang 2013 [9 ] Not found Low Not mentioned Random number table 3.58 (0.89, 14.39) OR 9.75 (1.16, 82.11) 6.02 (1.43, 25.40) 3.78 (1.29, 11.06) 2.83 (1.00, 7.98) 0.07 Shi 2010 [10 ] Not mentioned Low Not mentioned Not mentioned 3.86 (1.41, 10.57) 0.009 Li and Xu 2009 [11 ] Not mentioned Low Not mentioned Not mentioned 1.64 (0.51, 5.33) 0.41 L. Liu and Y. Liu 2014 [12 ] Not mentioned Low Not mentioned Random number table 2.62 (0.99, 6.94) 0.05 Ni et al. 2013 [13 ] Not found for intervention; rash and anaphylactoid purpura of legs for 1 case in control group; increase of eosinophil for 1 case Low Not mentioned Not mentioned 2.80 (1.35, 5.82) 0.006 Li 2013 [14 ] In intervention group, epigastric pain, fullness, belching, and poor appetite were all less than control group Low Not mentioned Not mentioned 3.62 (0.90, 14.63) 0.07 Tang and Hong 2003 [15 ] Most in control group, poor appetite, upper abdominal discomfort, nausea and vomiting, and so forth; especially used metronidazole, must add metoclopramide and anisodamine, and so forth, impacted quality of lives Low Not mentioned Not mentioned 1.58 (0.25, 9.95) 0.63