Metabolomics Analysis of Seminal Plasma in Infertile Males with Kidney-Yang Deficiency: A Preliminary Study
Table 2
Identified discriminating metabolites in positive mode.
VIP
Retention time (min)
Name
-test
Fold change*
1.35
141.1077
1.111
2-Keto-6-aminocaproic acid
0.024
0.688
1.75
135.0727
1.168
2-Phenylacetamide
0.001
−0.283
1.965
182.0816
1.168
Mannitol
0
−0.328
1.902
164.0516
1.168
Phenylpyruvic acid
0
−0.316
1.869
181.0787
1.168
Tyrosine
0
−0.312
1.607
607.0912
1.168
UDP-N-acetyl-D-galactosamine
0.006
−0.374
1.553
232.114
1.283
4-(Glutamylamino) butanoate
0.006
−1.937
1.443
215.1456
4.848
Pantothenic acid
0.013
0.617
1.372
515.2961
11.163
Taurocholic acid
0.029
1.038
1.861
352.2334
11.514
PGE2
0.001
−0.544
1.545
273.2751
14.728
C16 sphinganine
0.007
−0.427
2.749
287.2907
15.192
C17 sphinganine
0
−2.162
1.71
301.3064
15.54
Sphinganine
0.002
−0.42
1.545
330.341
16.062
Clupanodonic acid
0.007
−0.374
1.493
392.2982
17.603
Deoxycholic acid
0.01
−0.635
1.22
327.2855
17.75
N-palmitoyl alanine
0.048
−0.327
1.293
281.2798
17.751
Oleamide
0.033
−0.342
2.068
337.3424
17.864
Docosenamide
0
−1.448
Fold change was calculated as the ratio of the mean metabolite levels between two groups. A positive value of fold change indicates a relatively higher concentration of metabolites while a negative value of fold change indicates a relatively lower concentration in infertile males with KYDS as compared to fertile males.
