Figure 5: Representative micrographs of mitochondrial ultrastructure from convoluted proximal tubules. (a) Normal mitochondria structure in epithelial cell from convoluted proximal tubule from control rat. (b) In contrast, mitochondria show total cristae effacement in an animal treated with GM. (c) Convoluted proximal epithelial cell from a rat treated with CUR + GM shows numerous mitochondria with well-preserved morphology. (d) Similar mitochondrial morphology to CT animal is observed in rat only treated with CUR.