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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 921306, 10 pages
Research Article

Xanthohumol Induces Growth Inhibition and Apoptosis in Ca Ski Human Cervical Cancer Cells

Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia

Received 10 December 2014; Revised 5 February 2015; Accepted 25 February 2015

Academic Editor: Abid Hamid

Copyright © 2015 Wai Kuan Yong and Sri Nurestri Abd Malek. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [12 citations]

The following is the list of published articles that have cited the current article.

  • Yue Zhou, Jie Zheng, Ya Li, Dong-Ping Xu, Sha Li, Yu-Ming Chen, and Hua-Bin Li, “Natural Polyphenols for Prevention and Treatment of Cancer,” Nutrients, vol. 8, no. 8, pp. 515, 2016. View at Publisher · View at Google Scholar
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  • Zu-Qing Su, Yu-Hong Liu, Hui-Zhen Guo, Chao-Yue Sun, Jian-Hui Xie, Yu-Cui Li, Jian-Nan Chen, Xiao-Ping Lai, Zi-Ren Su, and Hai-Ming Chen, “Effect-enhancing and toxicity-reducing activity of usnic acid in ascitic tumor-bearing mice treated with bleomycin,” International Immunopharmacology, vol. 46, pp. 146–155, 2017. View at Publisher · View at Google Scholar
  • Zhaonan Ban, Hao Qin, Andrew J. Mitchell, Baoxiu Liu, Fengxia Zhang, Jing-Ke Weng, Richard A. Dixon, and Guodong Wang, “ Noncatalytic chalcone isomerase-fold proteins in Humulus lupulus are auxiliary components in prenylated flavonoid biosynthesis ,” Proceedings of the National Academy of Sciences, pp. 201802223, 2018. View at Publisher · View at Google Scholar
  • Chuan-Hao Jiang, Tao-Li Sun, Da-Xiong Xiang, Shan-Shan Wei, and Wen-Qun Li, “Anticancer Activity and Mechanism of Xanthohumol: A Prenylated Flavonoid From Hops (Humulus lupulus L.),” Frontiers in Pharmacology, vol. 9, 2018. View at Publisher · View at Google Scholar
  • Alka Jaudan, Sapna Sharma, Sri Nurestri Abd Malek, and Aparna Dixit, “Induction of apoptosis by pinostrobin in human cervical cancer cells: Possible mechanism of action,” Plos One, vol. 13, no. 2, pp. e0191523, 2018. View at Publisher · View at Google Scholar
  • Alexandre M. Carmo, Mónica A. Castro, Luís F. Guido, Daniel O. Carvalho, Jaime Freitas, Patrícia Nogueira, and Sónia N. Henriques, “Xanthohumol inhibits cell proliferation and induces apoptosis in human thyroid cells,” Food and Chemical Toxicology, vol. 121, pp. 450–457, 2018. View at Publisher · View at Google Scholar
  • Dongli Guo, Meng Jin, Baogui Zhang, and Shiqi Liu, “Xanthohumol induces apoptosis via caspase activation, regulation of Bcl-2, and inhibition of PI3K/Akt/mTOR-kinase in human gastric cancer cells,” Biomedicine and Pharmacotherapy, vol. 106, pp. 1300–1306, 2018. View at Publisher · View at Google Scholar
  • Facundo Vitelli Storelli, Antonio José Molina, Raul Zamora-Ros, Tania Fernández-Villa, Vasiliki Roussou, Dora Romaguera, Nuria Aragonés, Mireia Obón-Santacana, Marcela Guevara, Inés Gómez-Acebo, Guillermo Fernández-Tardón, Ana Molina-Barceló, Rocío Olmedo-Requena, Rocío Capelo, María Dolores Chirlaque, Beatriz Pérez-Gómez, Victor Moreno, Jesús Castilla, María Rubín-García, Marina Pollán, Manolis Kogevinas, Juan Pablo Barrio Lera, and Vicente Martín, “Flavonoids and the Risk of Gastric Cancer: An Exploratory Case-Control Study in the MCC-Spain Study,” Nutrients, vol. 11, no. 5, pp. 967, 2019. View at Publisher · View at Google Scholar