Evaluation of Antifungal Activity and Mode of Action of New Coumarin Derivative, 7-Hydroxy-6-nitro-2H-1-benzopyran-2-one, against Aspergillus spp.

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td align="left" rowspan="2">
 Drugs</td><td align="center" colspan="2">MIC alone</td><td align="center" colspan="2">Combined MIC (Cou-NO2)</td></tr><tr class="thead"><td align="center">A. fumigatus  ATCC 46913</td><td align="center">A. flavus  ATCC 16013</td><td align="center">A. fumigatus  ATCC 46913</td><td align="center">A. flavus  ATCC 16013</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td align="left">Amphotericin B</td><td align="center">2</td><td align="center">2</td><td align="center">2</td><td align="center">2</td></tr><tr><td align="left">Fluconazole</td><td align="center">256</td><td align="center">256</td><td align="center">128</td><td align="center">128</td></tr><tr><td align="left">Itraconazole</td><td align="center">128</td><td align="center">128</td><td align="center">32</td><td align="center">128</td></tr><tr><td align="left">Voriconazole</td><td align="center">4</td><td align="center">2</td><td align="center">0,5</td><td align="center">1</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

MIC values of antifungals in the absence and presence of coumarin derivative, 7-hydroxy-6-nitro-2H-1-benzopyran-2-one, MIC/8, against Aspergillus spp.

Evidence-Based Complementary and Alternative Medicine

tab3

Table 3

Table 3: Evaluation of Antifungal Activity and Mode of Action of New Coumarin Derivative, 7-Hydroxy-6-nitro-2H-1-benzopyran-2-one, against Aspergillus spp.

Table 3 | Evaluation of Antifungal Activity and Mode of Action of New Coumarin Derivative, 7-Hydroxy-6-nitro-2H-1-benzopyran-2-one, against Aspergillus spp. 