Table 3: MIC values of antifungals in the absence and presence of coumarin derivative, 7-hydroxy-6-nitro-2H-1-benzopyran-2-one, MIC/8, against Aspergillus spp.

DrugsMIC aloneCombined MIC (Cou-NO2)
A. fumigatus
ATCC 46913
A. flavus
ATCC 16013
A. fumigatus
ATCC 46913
A. flavus
ATCC 16013

Amphotericin B2222
Fluconazole256256128128
Itraconazole12812832128
Voriconazole420,51