The Protective Effect of Lacidipine on Myocardial Remodeling Is Mediated by the Suppression in Expression of GPR78 and CHOP in Rats

Table 3

Semiquantitative analysis of GRP78 and CHOP expression in myocardial tissue detected by immunohistochemistry.

Group	GRP78 (optical density)	CHOP (optical density)
Normal blank group	0.25 ± 0.02	0.08 ± 0.02
SHR control group	0.36 ± 0.04^*	0.49 ± 0.07^*
Captopril positive control group	0.29 ± 0.02^#	0.25 ± 0.03^#
Lacidipine 1.44 mg/kg group	0.31 ± 0.03	0.32 ± 0.04
Lacidipine 0.72 mg/kg group	0.30 ± 0.02^#	0.27 ± 0.03^#
Lacidipine 0.36 mg/kg group	0.33 ± 0.03	0.36 ± 0.04

< 0.05 compared with normal blank group; ^# < 0.05 compared with SHR control group.