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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 947619, 11 pages
Review Article

Chemical Components and Cardiovascular Activities of Valeriana spp.

1Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China
2Hubei University of Traditional Chinese Medicine, Wuhan, Hubei 430062, China
3Department of Pharmaceutical Chemistry, Beijing Institute of Radiation Medicine, Beijing 100850, China
4Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin, Heilongjiang 150036, China

Received 29 September 2015; Revised 16 November 2015; Accepted 19 November 2015

Academic Editor: William C. Cho

Copyright © 2015 Heng-Wen Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Valeriana spp. is a flowering plant that is well known for its essential oils, iridoid compounds such as monoterpenes and sesquiterpenes, flavonoids, alkaloids, amino acids, and lignanoids. Valeriana spp. exhibits a wide range of biological activities such as lowering blood pressure and heart rate, antimyocardial ischemia reperfusion injury, antiarrhythmia, and regulation of blood lipid levels. This review focuses on the chemical constituents and cardiovascular activities of Valeriana spp.