A Double-Blind Placebo-Controlled Trial of Maca Root as Treatment for Antidepressant-Induced Sexual Dysfunction in Women
Table 2
Subjects reaching improvement threshold on MGH-SFQa items by the last visit, by treatment and menopausal status (based on the number of subjects above the threshold at baseline).
Item rated “minimally diminished” or better (1–3) by last visit
Menopausal status
Maca
Placebo
Maca/placebo relative riskd
Maca/placebo odds ratio (95% CI)e
Number needed to treat (NNT)f
(%)c remitted
(%)c remitted
Item 1
Before
11
3 (27.27)
14
5 (35.71)
0.764
0.675 (0.121–3.767)
12 (NNH)g
Interest
After
5
2 (40.00)
4
2 (50.00)
0.800
0.667 (0.047–9.473)
10 (NNH)g
Item 2
Before
13
8 (61.54)
15
4 (26.67)
2.307
4.400 (0.889–21.781)
3
Arousal
After
5
2 (40.00)
4
2 (50.00)
0.800
0.667 (0.047–9.473)
10 (NNH)g
Item 3
Before
12
4 (33.33)
15
5 (33.33)
1.000
1.000 (0.200–5.004)
—
Orgasm
After
7
4 (50.00)
5
0 (0.0)
—
10.561 (1.027–108.641)
2
Item 4
Before
13
5 (38.46)
15
5 (33.33)
1.154
1.250 (0.265–5.886)
19
Satisfaction
After
6
3 (50.00)
4
2 (50.00)
1.000
1.000 (0.080–12.558)
—
MGH-SFQ: Massachusetts General Hospital-Sexual Functioning Questionnaire. : the number of subjects who were above the threshold at baseline. cPercentages are shown to 2 decimal places, for greater accuracy in computing relative risk, odds ratio, and NNT. dRelative risk is calculated by maca %/placebo % reaching the benefit threshold. eSee footnote e, Table 1. fSee footnote f, Table 1. gSee footnote g, Table 1.