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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 978219, 8 pages
Research Article

The Hepatoprotective Effect of Haoqin Qingdan Decoction against Liver Injury Induced by a Chemotherapeutic Drug Cyclophosphamide

Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, 314 An Shan Xi Dao, Nan Kai District, Tianjin 300193, China

Received 12 March 2015; Revised 29 April 2015; Accepted 3 May 2015

Academic Editor: Yibin Feng

Copyright © 2015 Xiaojiang Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Low, moderate or high dose of HQQD alone could significant reduce the tumor weight as compared with the control mice which suggested an effectiveness of HQQD (Fig S1A), though the inhibition rate was lower than CP administration (Fig S1B). Meanwhile, CP suppressed the thymus (Fig S1C) and spleen index (Fig S1D) which were reversed by individual use of HQQD. These results indicated a protective effect of HQQD alone on CP injury. Data displayed as mean of 10 mice in each group. The experiment was independently repeated for 3 times. **p < 0.01 versus model group, ***p < 0.001 versus model group; #p < 0.05 versus CP group, ##p < 0.01 versus CP group, ###p < 0.001 versus CP group.

  1. Supplementary Material