Yangjing Capsule Ameliorates Spermatogenesis in Male Mice Exposed to Cyclophosphamide

Table 1

Effects of YC on characteristics of sperm, seminiferous tubules, serum testosterone, body weight, and the relative testicular and epididymal weights.

Parameters	Control	CP	CP + YC (630 mg/kg)	CP + YC (1260 mg/kg)
Sperm count (×10^6 mL^−1)	82.56 ± 7.49	43.94 ± 4.70	51.31 ± 2.67	65.11 ± 8.18
Sperm motility (%)	69.00 ± 6.22	45.76 ± 7.28	62.22 ± 4.68	65.25 ± 7.06
Proportion of damaged tubules (%)	2.9 ± 2.3	75.1 ± 5.3	20.5 ± 7.6	13.3 ± 6.1
Body weight (g)	29.11 ± 1.54	26.0 ± 1.41	26.50 ± 1.41	28.11 ± 1.76
Relative testicular weight (mg/g bodyweight)	4.02 ± 0.28	2.75 ± 0.54	3.13 ± 0.29	3.32 ± 0.39
Relative epididymal weight (mg/g bodyweight)	1.47 ± 0.20	1.10 ± 0.11	1.44 ± 0.13	1.37 ± 0.12
Testosterone (mol/L)	1.81 ± 0.86	0.56 ± 0.22	0.61 ± 0.26	0.76 ± 0.35

Data are expressed as the mean ± SD (). , compared to the control group; , compared to the CP-treated group.
CP: cyclophosphamide; SD: standard deviation; YC: Yangjing capsule.