Additive Effect of Qidan Dihuang Grain, a Traditional Chinese Medicine, and Angiotensin Receptor Blockers on Albuminuria Levels in Patients with Diabetic Nephropathy: A Randomized, Parallel-Controlled Trial
Table 4
Significant differences in 11 specific Traditional Chinese Medicine Symptom (TCMS) scores.
TCMS
Week
Treatment group
Control group
value
()
()
Thirst and need to drink water
0
1 (1.00, 2.00)
1 (1.00, 1.75)
0.289
0.773
4
0 (0.00, 2.00)
1 (1.00, 1.00)
1.639
0.101
8
0 (0.00, 1.00)
1 (0.00, 1.00)
2.757
0.006
12
0 (0.00, 1.00)
1 (0.00, 1.00)
2.786
0.005
Shortness of breath and disinclination to talk
0
0 (0.00, 1.00)
1 (0.00, 1.00)
1.266
0.205
4
0 (0.00, 1.00)
1 (0.00, 1.00)
2.586
0.010
8
0 (0.00, 0.00)
0 (0.00, 1.00)
2.204
0.028
12
0 (0.00, 0.00)
0 (0.00, 1.00)
2.164
0.030
Lassitude and lack of strength
0
1 (0.00, 1.00)
1 (0.00, 1.00)
0.498
0.618
4
1 (0.00, 1.00)
1 (0.25, 1.00)
1.675
0.094
8
0 (0.00, 1.00)
1 (0.00, 1.00)
1.874
0.061
12
0 (0.00, 1.00)
1 (0.00, 1.00)
2.347
0.019
Profuse sweating
0
1 (0.00, 1.00)
1 (0.00, 1.00)
0.014
0.989
4
0 (0.00, 1.00)
1 (0.00, 1.00)
2.944
0.003
8
0 (0.00, 1.00)
1 (0.00, 1.00)
3.377
0.001
12
0 (0.00, 0.00)
1 (0.00, 1.00)
4.060
0.000
Inability to sleep
0
1 (0.00, 1.00)
1 (0.00, 1.00)
0.237
0.812
4
0 (0.00, 1.00)
1 (0.00, 1.00)
1.555
0.120
8
0 (0.00, 1.00)
1 (0.00, 1.00)
2.081
0.037
12
0 (0.00, 1.00)
1 (0.00, 1.00)
2.188
0.029
Weakness of waist and knees
0
1 (1.00, 1.00)
1 (0.25, 1.00)
0.233
0.816
4
0 (0.00, 1.00)
1 (0.00, 1.00)
1.716
0.086
8
0 (0.00, 1.00)
1 (0.00, 1.00)
2.057
0.040
12
0 (0.00, 1.00)
1 (0.00, 1.00)
2.647
0.008
Abdominal distension
0
0 (0.00, 0.00)
0 (0.00, 0.75)
1.112
0.911
4
0 (0.00, 0.00)
0 (0.00, 1.00)
2.403
0.016
8
0 (0.00, 0.00)
0 (0.00, 1.00)
2.598
0.009
12
0 (0.00, 0.00)
0 (0.00, 1.00)
2.042
0.041
Frequent and excessive urination
0
1 (0.00, 1.00)
1 (0.00, 1.00)
0.621
0.534
4
0 (0.00, 1.00)
1 (1.00, 1.00)
1.673
0.094
8
0 (0.00, 1.00)
1 (0.25, 1.00)
2.513
0.012
12
0 (0.00, 1.00)
1 (0.00, 1.00)
2.607
0.009
Frequent urination at night
0
1 (0.00, 2.00)
1 (1.00, 1.00)
0.189
0.850
4
1 (0.00, 1.00)
1 (1.00, 1.00)
1.145
0.252
8
0 (0.00, 1.00)
1 (0.00, 1.00)
2.085
0.037
12
0 (0.00, 1.00)
1 (0.00, 1.00)
2.115
0.034
Uncomfortable with defecation
0
0 (0.00, 0.00)
0 (0.00, 0.00)
0.476
0.634
4
0 (0.00, 0.00)
0 (0.00, 1.00)
1.975
0.048
8
0 (0.00, 0.00)
0 (0.00, 1.00)
3.114
0.002
12
0 (0.00, 0.00)
0 (0.00, 1.00)
2.984
0.003
Frequent and excessive number of stools
0
0 (0.00, 0.00)
0 (0.00, 0.00)
1.116
0.264
4
0 (0.00, 0.00)
0 (0.00, 0.00)
1.972
0.049
8
0 (0.00, 0.00)
0 (0.00, 0.00)
2.214
0.027
12
0 (0.00, 0.00)
0 (0.00, 0.75)
2.374
0.018
Data are expressed as median (interquartile range). values represent the treatment group versus the control group. represent versus baseline (week 0), Wilcoxon matched-pairs signed-rank test for nonnormal distribution.
