Dual-Directional Immunomodulatory Effects of Corbrin Capsule on Autoimmune Thyroid Diseases
Table 2
Baseline characteristics of subjects.
GD
HT
Tx
Ct
value
Tx ()
Ct ()
value
Age (year)
36.2 14.19
37.24 10.26
0.156
41.40 13.76
43.82 12.48
0.168
Gender (male/female)
14/28
6/16
0.492
11/39
7/17
0.254
BMI (kg/m2)
21.11 2.46
22.94 3.16
0.061
23.13 3.57
22.83 4.01
0.071
SBP (mmHg)
117.87 12.26
114.55 11.43
0.112
120.25 15.24
114.27 17.64
0.057
DBP (mmHg)
76.47 10.23
78.58 9.15
0.135
86.08 13.44
77.98 10.21
0.106
HR (/min)
88.53 5.82
86.89 4.53
0.171
75.42 9.32
78.36 8.34
0.770
FT3 (pmol/L)
9.52 7.53
8.96 1.43
0.308
3.39 1.01
3.42 1.12
0.640
FT4 (pmol/L)
23.01 17.26
25.93 10.46
0.112
11.83 3.64
10.47 3.59
0.318
TSH (IU/L)
0.07 0.13
0.09 0.17
0.451
10.94 6.52
9.75 7.21
0.522
TPO-Ab (IU/mL)
659.28 585.89
672.39 463.51
0.086
820.51 372.45
829.39 388.29
0.455
TG-Ab (IU/mL)
—
—
—
547.8 331.45
593.28 273.65
0.383
TR-Ab (IU/mL)
34.51 17.97
31.16 11.46
0.128
—
—
—
CD3+ (%)
66.98 9.40
67.62 8.36
0.196
69.56 8.57
67.62 8.36
0.146
CD4+ (%)
38.30 5.37
36.96 2.29
0.227
34.47 6.74
33.96 4.29
0.238
CD8+ (%)
21.93 4.46
21.98 6.56
0.348
29.07 7.06
28.98 6.54
0.074
CD4+/CD8+ ratio
1.86 0.66
1.89 0.79
0.105
1.23 0.55
1.19 0.68
0.089
44 Graves disease (GD) outpatients and 56 hypothyroid Hashimoto’s thyroiditis (HT) outpatients were newly definitely diagnosed and enrolled. All general data and thyroid hormones and related antibodies and cell immune indicators were listed. GD-Tx: GD treatment group; GD-Ct: GD control group; HT-Tx: HT treatment group; and HT-Ct: HT control group.
