Research Article

Investigation of Calcium Channel Blockers as Antiprotozoal Agents and Their Interference in the Metabolism of Leishmania (L.) infantum

Figure 2

ROS generation in promastigotes in the presence of amlodipine and fendiline. The ROS production was verified using the indicator 2′,7′-dichlorodihydrofluorescein diacetate (H2DCF-DA) after incubation with amlodipine and fendiline (20 μM). Nitazoxanide was used as positive control. () indicates significant difference relative to the untreated group (; ; ).