Investigation of Calcium Channel Blockers as Antiprotozoal Agents and Their Interference in the Metabolism of Leishmania (L.) infantum
ROS generation in promastigotes in the presence of amlodipine and fendiline. The ROS production was verified using the indicator 2′,7′-dichlorodihydrofluorescein diacetate (H2DCF-DA) after incubation with amlodipine and fendiline (20 μM). Nitazoxanide was used as positive control. () indicates significant difference relative to the untreated group (; ; ).
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