Membrane Stabilization and Detoxification of Acetaminophen-Mediated Oxidative Onslaughts in the Kidneys of Wistar Rats by Standardized Fraction of Zea mays L. (Poaceae), Stigma maydis
Table 3
Effect of Zea mays, Stigma maydis ethyl acetate fraction on serum concentrations of some kidney function parameters of acetaminophen-treated rats (, mean ± SEM).
Treatments
Creatinine (mg/dL)
BUN (mg/dL)
Uric acid (mg/dL)
CCR (mL/min)
Sterile placebo (control)
0.63 ± 0.02
15.66 ± 0.17
4.09 ± 0.01
10.48 ± 0.01
APAP treatment
2.50 ± 0.04
49.00 ± 0.26
15.99 ± 0.02
2.64 ± 0.01
200 mg/kg b.w. CSEAF
0.62 ± 0.01
14.99 ± 0.43
4.10 ± 0.03
10.65 ± 0.02
100 mg/kg b.w. CSEAF, then APAP
0.99 ± 0.03
22.11 ± 0.23
8.11 ± 0.09
6.67 ± 0.01
200 mg/kg b.w. CSEAF, then APAP
0.57 ± 0.02
15.99 ± 0.13
4.51 ± 0.03
11.58 ± 0.02
200 mg/kg b.w. vitamin C, then APAP
0.56 ± 0.02
16.00 ± 0.12
4.51 ± 0.09
11.79 ± 0.01
APAP, then 100 mg/kg b.w. CSEAF
1.11 ± 0.03
25.12 ± 0.18
8.99 ± 0.06
5.95 ± 0.02
APAP, then 200 mg/kg b.w. CSEAF
0.63 ± 0.05
15.79 ± 0.12
9.01 ± 0.06
10.48 ± 0.01
APAP, then 200 mg/kg b.w. vitamin C
1.25 ± 0.01
16.09 ± 0.23
8.88 ± 0.04
5.28 ± 0.01
Values with different superscripts for each parameter are significantly different (). APAP: acetaminophen, CSEAF: corn silk ethyl acetate fraction, BUN: blood urea nitrogen, and CCR: estimated creatinine clearance rate.
