Research Article

Membrane Stabilization and Detoxification of Acetaminophen-Mediated Oxidative Onslaughts in the Kidneys of Wistar Rats by Standardized Fraction of Zea mays L. (Poaceae), Stigma maydis

Table 4

Effect of Zea mays, Stigma maydis ethyl acetate fraction on serum concentrations of selected electrolytes of acetaminophen-treated rats (, mean ± SEM).

TreatmentsSodium (mEq/L)Potassium (mEq/L)Calcium (mg/dL)

Sterile placebo (control)135.44 ± 1.353.50 ± 1.018.95 ± 1.01
APAP treatment338.22 ± 1.6510.11 ± 1.023.33 ± 1.00
200 mg/kg b.w. CSEAF145.01 ± 1.213.59 ± 1.009.83 ± 1.02
100 mg/kg b.w. CSEAF, then APAP 198.22 ± 1.115.55 ± 1.025.99 ± 1.01
200 mg/kg b.w. CSEAF, then APAP 138.94 ± 1.263.75 ± 1.069.01 ± 1.00
200 mg/kg b.w. vitamin C, then APAP 143.12 ± 1.703.55 ± 1.019.17 ± 1.01
APAP, then 100 mg/kg b.w. CSEAF226.21 ± 1.137.09 ± 1.016.99 ± 1.02
APAP, then 200 mg/kg b.w. CSEAF200.12 ± 1.425.99 ± 1.008.99 ± 1.02
APAP, then 200 mg/kg b.w. vitamin C 139.01 ± 1.223.79 ± 1.029.15 ± 1.01

Values with different superscripts for each parameter are significantly different (). APAP: acetaminophen and CSEAF: corn silk ethyl acetate fraction.