Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2016, Article ID 2352614, 10 pages
http://dx.doi.org/10.1155/2016/2352614
Research Article

The Effect of Wenxin Keli on the mRNA Expression Profile of Rabbits with Myocardial Infarction

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Bei Li Shi Road, Xicheng District, Beijing 100037, China

Received 30 May 2016; Revised 14 August 2016; Accepted 22 September 2016

Academic Editor: Xiu-Min Li

Copyright © 2016 Min Zheng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Q. Xie, Z. Sun, M. Chen, Q. Zhong, T. Yang, and J. Yi, “IL-8 up-regulates proliferative angiogenesis in ischemic myocardium in rabbits through phosphorylation of Akt/GSK-3beta(ser9) dependent pathways,” International Journal of Clinical and Experimental Medicine, vol. 8, no. 8, pp. 12498–12508, 2015. View at Google Scholar
  2. K. Alexiou, M. Wilbring, C. Koch, U. Kappert, S. Tugtekin, and K. Matschke, “Midterm follow-up of patients with perioperative myocardial infarction after coronary artery bypass surgery: Clinical significance of different treatment strategies,” Thoracic and Cardiovascular Surgeon, vol. 60, no. 7, pp. 452–461, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. Y. Chen, X. Xiong, C. Wang et al., “The effects of wenxin keli on left ventricular ejection fraction and brain natriuretic peptide in patients with heart failure: a meta-analysis of randomized controlled trials,” Evidence-Based Complementary and Alternative Medicine, vol. 2014, Article ID 242589, 9 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  4. Y. Chen, Y. Li, L. Guo et al., “Effects of Wenxin Keli on the action potential and L-type calcium current in rats with transverse aortic constriction-induced heart failure,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 572078, 12 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  5. X. Wang, X. Wang, Y. Gu, T. Wang, and C. Huang, “Wenxin Keli attenuates ischemia-induced ventricular arrhythmias in rats: involvement of L-type calcium and transient outward potassium currents,” Molecular Medicine Reports, vol. 7, no. 2, pp. 519–524, 2013. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Burashnikov, A. Petroski, D. Hu, H. Barajas-Martinez, and C. Antzelevitch, “Atrial-selective inhibition of sodium-channel current by Wenxin Keli is effective in suppressing atrial fibrillation,” Heart Rhythm, vol. 9, no. 1, pp. 125–131, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. Y. Xing, Y. Gao, J. Chen et al., “Wenxin-Keli regulates the calcium/calmodulin-dependent protein kinase II signal transduction pathway and inhibits cardiac arrhythmia in rats with myocardial infarction,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 464508, 15 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  8. S.-H. Li, H.-L. Yang, H. Xiao, Y.-B. Wang, D.-C. Wang, and R. Huo, “Inflammation and cutaneous nervous system involvement in hypertrophic scarring,” Neural Regeneration Research, vol. 10, no. 10, pp. 1678–1682, 2015. View at Publisher · View at Google Scholar · View at Scopus
  9. S. Gabriel and B. Geetha, “The renin-angiotensin-aldosterone system and heart failure,” Cardiology Clinics, vol. 32, no. 1, pp. 21–32, 2014. View at Google Scholar
  10. M. Ieda, K. Fukuda, Y. Hisaka et al., “Endothelin-1 regulates cardiac sympathetic innervation in the rodent heart by controlling nerve growth factor expression,” The Journal of Clinical Investigation, vol. 113, no. 6, pp. 876–884, 2004. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Makowski, P. Lenartowicz, B. Oszywa, M. Jewgiński, M. Pawełczak, and P. Kafarski, “Synthesis of dehydrodipeptide esters and their evaluation as inhibitors of cathepsin C,” Medicinal Chemistry Research, vol. 24, no. 8, pp. 3157–3165, 2015. View at Publisher · View at Google Scholar · View at Scopus
  12. Y. Xiong, L. Wang, W. Deng, J. Wang, and T. Shi, “Human TTC5, a novel tetratricopeptide repeat domain containing gene, activates p53 and inhibits AP-1 pathway,” Molecular Biology Reports, vol. 40, no. 11, pp. 6183–6188, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. P. Wei, X. J. Yang, Q. Fu et al., “Intermedin attenuates myocardial infarction through activation of autophagy in a rat model of ischemic heart failure via both cAMP and MAPK/ERK1/2 pathways,” International Journal of Clinical and Experimental Pathology, vol. 8, no. 9, pp. 9836–9844, 2015. View at Google Scholar
  14. A. Yndestad, J. K. Damås, E. Øie, T. Ueland, L. Gullestad, and P. Aukrust, “Role of inflammation in the progression of heart failure,” Current Cardiology Reports, vol. 9, no. 3, pp. 236–241, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. A. Wu, J. Zhai, D. Zhang et al., “Effect of wenxin granule on ventricular remodeling and myocardial apoptosis in rats with myocardial infarction,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 967986, 10 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. Y. Yu, S. G. Wei, Z. H. Zhang, R. M. Weiss, and R. B. Felder, “ERK1/2 MAPK signaling in hypothalamic paraventricular nucleus contributes to sympathetic excitation in rats with heart failure after myocardial infarction,” American Journal of Physiology—Heart and Circulatory Physiology, vol. 310, no. 6, pp. H732–H739, 2016. View at Publisher · View at Google Scholar
  17. K. T. Lappegård, H. Bjørnstad, T. E. Mollnes, and A. Hovland, “Effect of cardiac resynchronization therapy on inflammation in congestive heart failure: a review,” Scandinavian Journal of Immunology, vol. 82, no. 3, pp. 191–198, 2015. View at Publisher · View at Google Scholar · View at Scopus
  18. S. S. Gottlieb, K. Harris, J. Todd et al., “Prognostic significance of active and modified forms of endothelin 1 in patients with heart failure with reduced ejection fraction,” Clinical Biochemistry, vol. 48, no. 4-5, pp. 292–296, 2015. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Adamopoulos, J. Parissis, C. Kroupis et al., “Physical training reduces peripheral markers of inflammation in patients with chronic heart failure,” European Heart Journal, vol. 22, no. 9, pp. 791–797, 2001. View at Publisher · View at Google Scholar · View at Scopus
  20. D. R. Greaves, T. Häkkinen, A. D. Lucas et al., “Linked chromosome 16q13 chemokines, macrophage-derived chemokine, fractalkine, and thymus- and activation-regulated chemokine, are expressed in human atherosclerotic lesions,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 21, no. 6, pp. 923–929, 2001. View at Publisher · View at Google Scholar · View at Scopus
  21. L. Poupel, A. Boissonnas, P. Hermand et al., “Pharmacological inhibition of the chemokine receptor, CX3CR1, reduces atherosclerosis in mice,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 33, no. 10, pp. 2297–2305, 2013. View at Publisher · View at Google Scholar · View at Scopus
  22. A. Niessner, R. Marculescu, H. Kvakan et al., “Fractalkine receptor polymorphisms V2491 and T280M as genetic risk factors for restenosis,” Thrombosis and Haemostasis, vol. 94, no. 6, pp. 1251–1256, 2005. View at Publisher · View at Google Scholar · View at Scopus
  23. C.-Y. Peng, T.-H. Chen, Y.-P. Lim et al., “Association of MRC-1 and IL-28B with the treatment outcome of hepatitis C: a case control study,” BMC Gastroenterology, vol. 14, article 113, 2014. View at Publisher · View at Google Scholar · View at Scopus
  24. C. F. Wenceslau, C. G. McCarthy, T. Szasz, S. Goulopoulou, and R. C. Webb, “Mitochondrial N-formyl peptides induce cardiovascular collapse and sepsis-like syndrome,” American Journal of Physiology—Heart and Circulatory Physiology, vol. 308, no. 7, pp. H768–H777, 2015. View at Publisher · View at Google Scholar · View at Scopus
  25. G. Shao, M. W. Julian, S. Bao et al., “Formyl peptide receptor ligands promote wound closure in lung epithelial cells,” American Journal of Respiratory Cell and Molecular Biology, vol. 44, no. 3, pp. 264–269, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. M. P. Nanut, J. Sabotič, A. Jewett, and J. Kos, “Cysteine cathepsins as regulators of the cytotoxicity of NK and T cells,” Frontiers in Immunology, vol. 5, article 616, 2014. View at Publisher · View at Google Scholar · View at Scopus
  27. O. Kazanskaya, B. Ohkawara, M. Heroult et al., “The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development,” Development, vol. 135, no. 22, pp. 3655–3664, 2008. View at Publisher · View at Google Scholar · View at Scopus
  28. X. Liu, Y. Zhang, W. Du et al., “MiR-223-3p as a novel MicroRNA regulator of expression of voltage-gated K+ channel Kv4.2 in acute myocardial infarction,” Cellular Physiology and Biochemistry, vol. 39, no. 1, pp. 102–114, 2016. View at Google Scholar