Radix Astragali-Based Chinese Herbal Medicine for Oxaliplatin-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis

Table 1

Grading scales used to evaluate oxaliplatin-induced peripheral neuropathy.

	Grade 1	Grade 2	Grade 3	Grade 4
Levi et al. [31]	Paresthesia or insensitive, complete relief in 1 week	Paresthesia or insensitive, complete relief in 14 days	Paresthesia or insensitive, complete relief in 21 days	Paresthesia or insensitive,; combined with functional abnormality
Miller et al. [32]	Paresthesias and/or decreased tendon reflex	Severe paresthesia and/or mild anergia	Intolerable paresthesia and/or marked motor loss	Paralysis
CTCAE 4.03 [33]	Asymptomatic; loss of deep tendon reflexes or paresthesia	Moderate symptoms; limiting instrumental ADL	Severe symptoms; limiting self-care ADL	Life-threatening consequences; urgent intervention indicated