Modes of Antiviral Action of Chemical Portions and Constituents from Woad Root Extract against Influenza Virus A FM1
Table 1
Effect of prophylactic treatment on the viability and protection rate of MDCK cells.
Groups
OD560
Protection rate (%)
1 : 2
1 : 4
1 : 8
1 : 16
1 : 2
1 : 4
1 : 8
1 : 16
CB (50 μg/mL)
2.126 ± 0.034
2.228 ± 0.167
2.284 ± 0.017
2.218 ± 0.011
188.348
199.08
205.023
198.08
Epigoitrin (50 μg/mL)
2.197 ± 0.152
2.239 ± 0.050
2.202 ± 0.102
2.041 ± 0.036
195.871
200.29
196.344
214.435
PEP portion (1 mg/mL)
2.840 ± 0.150
2.464 ± 0.024
2.407 ± 0.048
2.149 ± 0.069
263.467
223.91
217.912
190.821
PEP + ALK + OA (1 mg/mL)
2.698 ± 0.082
2.090 ± 0.042
2.045 ± 0.089
2.171 ± 0.028
248.58
184.61
179.879
193.135
Ribavirin (100 μg/mL)
1.866 ± 0.251
1.924 ± 0.306
1.614 ± 0.086
1.869 ± 0.016
161.047
167.1
134.245
161.31
Virus control
0.335 ± 0.073
Cell control
1.286 ± 0.277
PEP: phenylpropanoids portion; PEP + ALK + OA: the mixtures of phenylpropanoids, alkaloids, and organic acid portions. Cell control: normal cells without virus infection and drug treatments. Virus control: cells infected with influenza A FM1 virus. Data of OD560 was mean ± SD. The asterisks indicate a significant difference between the test samples and the virus control according to Student’s t-test. .
