Effects of Shenfu Injection in the Treatment of Septic Shock Patients: A Multicenter, Controlled, Randomized, Open-Label Trial

Table 2

Clinical indexes during treatment.

	Shenfu	Controls	value
48 h
Blood glucose (mmol/L)	9.01 ± 6.33	7.81 ± 3.07	0.134
PT (s)	14.20 ± 3.63	14.39 ± 7.51	0.858
APTT (s)	37.28 ± 9.00	36.76 ± 9.81	0.749
Fibrinogen (g/dL)	3.76 ± 1.64	4.60 ± 6.12	0.304
BUN	10.44 ± 7.86	9.28 ± 7.10	0.346
Cr	101.16 ± 71.98	104.94 ± 94.68	0.784
ALT	78.51 ± 140.56	54.96 ± 54.54	0.165
AST	102.29 ± 161.02	74.46 ± 91.01	0.235
WBC	13.33 ± 9.61	12.06 ± 10.22	0.422
RBC	3.40 ± 0.68	3.75 ± 1.01	0.012
HCT	30.66 ± 6.28	31.71 ± 7.31	0.331
Platelets (×10^9/L)	108.49 ± 75.42	115.31 ± 81.19	0.585
48 h
CVP (cmH2O)	10.67 ± 4.46	6.35 ± 3.16	0.018
ScvO2	79.63 ± 13.28	54.70 ± 28.81	0.017
6 d
Arterial lactate (mmol/L)	2.37 ± 2.81	2.60 ± 2.52	0.533
Lactate clearance	−0.40 ± 0.59	−0.33 ± 0.39	0.369
24 h
APACHE 2	14.75 ± 9.13	15.14 ± 11.22	0.846
5 d
Urine output (mL/h)	91.91 ± 49.97	102.18 ± 40.25	0.274
6 d
Systolic pressure (mmHg)	33.88 ± 19.44	34.72 ± 25.97	0.851
Diastolic pressure (mmHg)	15.46 ± 16.25	13.12 ± 16.52	0.463
MAP (mmHg)	21.60 ± 15.82	20.32 ± 18.26	0.699
Heart rate (bpm)	−24.51 ± 21.78	−26.20 ± 26.74	0.719
Dose of dopamine (mg)	842.04 ± 835.81	1224.71 ± 1704.24	0.237
Number of dopamine uses			0.229
Dose of norepinephrine (mg)	72.67 ± 64.19	80.59 ± 137.68	0.759
Number of epinephrine uses			0.99
ICU day (day)	9.4 ± 11.3	9.1 ± 14.4	0.895
Total hospital day (day)	15.2 ± 13.7	14.1 ± 15.8	0.675

PT: prothrombin time; aPTT: activated partial prothrombin time; BUN: blood urea nitrogen; Cr: creatinine; ALT: alanine transaminase; AST: aspartate transaminase; WBC: white blood cells; RBC: red blood cells; HCT: hematocrit; CVP: central venous pressure; ScvO₂: central venous oxygen saturation; APACHE: acute physiology and chronic health evaluation; ICU: intensive care unit.