Effect of Kuijie Granule on the Expression of TGF-β/Smads Signaling Pathway in Patients with Ulcerative Colitis

Figure 4

Kuijie Granule increases the expression of Smad4 and decreases Smad7 in colon tissue of patients with UC. (a) and (b) show the data analysis results for Smad4 and Smad7 expression; there exist significant differences before and after Kuijie Granule treatment (); . ICH Histological Score means the integration of patients in Smad4 and Smad7 expression which come from the percentage of positive cells, 1 point: 0~10%, 2 points: 11%~25%, 3 points: 26%~75%, and 4 points: 76%~100%. (c) Representative images of the microscopic images obtained from colon tissues of patients with UC staining with anti-Smad4 and anti-Smad7.

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